SCHEMBL30520135

SCHEMBL30520135

CCOC(=O)[C@H](Br)CC(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
TRPA1 O75762 1/20 0.39
LMNA P02545 3/20 0.39
HSD17B10 Q99714 1/20 0.39
GAA P10253 2/20 0.37
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
MMP8 P22894 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
PPID Q08752 1/20 0.35
TSHR P16473 1/20 0.34
ZDHHC7 Q9NXF8 1/20 0.34
RNPEP Q9H4A4 1/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1370661 1.00 ALDH1A1 (0.40) ALDH1A1TRPA1LMNAHSD17B10GAA
SCHEMBL1286734 0.88 ALDH1A1 (0.46) ALDH1A1TRPA1LMNAHSD17B10GAA
SCHEMBL14016338 0.88 ALDH1A1 (0.46) ALDH1A1TRPA1LMNAHSD17B10GAA
SCHEMBL20332953 0.84 CYP3A4 (0.45) ALDH1A1TRPA1LMNAHSD17B10GAA
SCHEMBL12539120 0.84 CYP3A4 (0.45) ALDH1A1TRPA1LMNAHSD17B10GAA
SCHEMBL29045 0.83 ALDH1A1 (0.37) ALDH1A1TRPA1LMNAHSD17B10GAA
SCHEMBL6337519 0.81 ALDH1A1 (0.36) ALDH1A1TRPA1LMNAHSD17B10GAA
SCHEMBL18397555 0.80 ALDH1A1 (0.41) ALDH1A1TRPA1LMNAHSD17B10GAA
SCHEMBL10569161 0.80 ZDHHC7 (0.41) ALDH1A1TRPA1LMNAHSD17B10GAA
SCHEMBL20328792 0.80 ALDH1A1 (0.39) ALDH1A1TRPA1LMNAHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425682-A Pyrimidine-1 (2H) -oxo compound and preparation method and application thereof 深圳信立泰药业股份有限公司 2023-07-14 CN disclosed