SCHEMBL30521965

SCHEMBL30521965

CCCCCc1cc(CC=O)c(O)c(Cc2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 7/20 0.51
CNR2 P34972 7/20 0.51
PTPN1 P18031 2/20 0.43
PTPN2 P17706 1/20 0.43
PTPN6 P29350 1/20 0.43
GPR55 Q9Y2T6 1/20 0.41
PTGS2 P35354 3/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25346873 1.00 CNR1 (0.51) CNR1CNR2PTPN1PTPN2PTPN6
SCHEMBL30521967 0.90 CNR1 (0.43) CNR1CNR2PTPN1PTPN2PTPN6
SCHEMBL25346065 0.90 CNR1 (0.43) CNR1CNR2PTPN1PTPN2PTPN6
SCHEMBL9804713 0.87 CNR1 (0.55) CNR1CNR2PTGS2CYP3A4
SCHEMBL25345032 0.84 PTGS2 (0.49) PTGS2CYP3A4
SCHEMBL10869869 0.84 CNR1 (0.51) CNR1CNR2PTPN1PTPN2PTPN6
SCHEMBL25345188 0.83 PTPN1 (0.59) PTPN1PTPN2PTPN6
SCHEMBL30521971 0.83 PTPN1 (0.59) PTPN1PTPN2PTPN6
SCHEMBL25346311 0.83 CNR1 (0.52) CNR1CNR2PTPN1PTPN2PTPN6
SCHEMBL30521966 0.83 CNR1 (0.52) CNR1CNR2PTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116568291-A Substituted aromatic compounds and pharmaceutical compositions thereof 殷格纽制药有限公司 2023-08-08 CN claimed
US-20240043372-A1 SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF PHARMACEUTIQUE INGENEW INC. (CA) 2024-02-08 US disclosed
CN-116568291-A Substituted aromatic compounds and pharmaceutical compositions thereof 殷格纽制药有限公司 2023-08-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240043372-A1 SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF NR1H4, NR1H2, NR1H3 CNR1 8/4885CNR2 14/4885PTPN1 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.