Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.69 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.62 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29696550 | 0.82 | KEAP1 (1.00) | KEAP1PDPK1GRM5HDAC1HDAC2 | |
| SCHEMBL336234 | 0.82 | KEAP1 (1.00) | KEAP1PDPK1GRM5HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL8595147 | 0.80 | KEAP1 (0.96) | KEAP1PDPK1GRM5HDAC1HDAC2 | |
| SCHEMBL29567411 | 0.77 | PDPK1 (1.00) | KEAP1PDPK1GRM5HDAC1HDAC2 | |
| SCHEMBL3790885 | 0.77 | KEAP1 (0.70) | KEAP1PDPK1GRM5HDAC1HDAC2 | |
| SCHEMBL27967849 | 0.77 | KEAP1 (0.70) | KEAP1PDPK1GRM5HDAC1HDAC2 | |
| SCHEMBL30690400 | 0.77 | KEAP1 (0.70) | KEAP1PDPK1GRM5HDAC1HDAC2 | |
| SCHEMBL27968063 | 0.77 | KEAP1 (0.70) | KEAP1PDPK1GRM5HDAC1HDAC2 | |
| SCHEMBL1651352 | 0.77 | PDPK1 (1.00) | KEAP1PDPK1GRM5HDAC1HDAC2 | |
| SCHEMBL27968058 | 0.77 | KEAP1 (0.70) | KEAP1PDPK1GRM5HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031547-B | Indole compound and application thereof | 上海甘田光学材料有限公司 | 2023-05-30 | — | — | CN | disclosed |