Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HK1 | P19367 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1883788 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL1879533 | 1.00 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL1879715 | 0.88 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL1879716 | 0.88 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL7803071 | 0.87 | MAPT (0.54) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL6490375 | 0.86 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL6490384 | 0.86 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL1874543 | 0.86 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL1877131 | 0.86 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL1877477 | 0.86 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178243-A | Preparation method and application of (hetero) aryl fused carbazole compound | 西南医科大学 | 2023-05-30 | — | — | CN | disclosed |