Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30522367 | 1.00 | F2 (0.37) | F2HDAC3HDAC1HDAC2LMNA | |
| SCHEMBL30552702 | 0.76 | HDAC3 (0.37) | HDAC3HDAC1HDAC2 | |
| SCHEMBL14655635 | 0.69 | HDAC3 (0.33) | HDAC3HDAC1HDAC2 | |
| SCHEMBL18517436 | 0.68 | HDAC4 (0.36) | HDAC3HDAC1HDAC2 | |
| SCHEMBL20899890 | 0.68 | HDAC3 (0.35) | HDAC3HDAC1HDAC2 | |
| SCHEMBL31418257 | 0.67 | SPR (0.36) | HDAC3HDAC1HDAC2 | |
| SCHEMBL22964438 | 0.67 | — | — | |
| SCHEMBL16600541 | 0.67 | HDAC3 (0.34) | HDAC3HDAC1HDAC2 | |
| SCHEMBL12001421 | 0.67 | SMN1; SMN2 (0.45) | HDAC3HDAC1HDAC2 | |
| SCHEMBL29889210 | 0.66 | SPR (0.46) | HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178345-B | Substituted pyrimidinyl-pyridinyl-pyridone compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-116178345-A | Substituted pyrimidinyl-pyridinyl-pyridone compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-05-30 | — | — | CN | disclosed |