SCHEMBL305225

SCHEMBL305225

Brc1ccccc1C(Br)Br

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43
ALDH1A1 P00352 5/20 0.39
HTT P42858 1/20 0.37
CYP2C19 P33261 3/20 0.37
CYP2C9 P11712 2/20 0.37
CYP1A2 P05177 1/20 0.37
MAPK1 P28482 1/20 0.36
OPRL1 P41146 2/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
CFTR P13569 2/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL655520 0.81 CYP1A2 (0.43) IDO1TDO2ALDH1A1HTTCYP2C19
SCHEMBL4087851 0.79 IDO1 (0.45) IDO1TDO2ALDH1A1HTTCYP2C19
SCHEMBL608330 0.78 CFTR (0.41) IDO1TDO2ALDH1A1HTTCYP2C19
SCHEMBL3171505 0.78 IDO1 (0.45) IDO1TDO2ALDH1A1HTTCYP2C19
SCHEMBL3293339 0.78 HTT (0.43) IDO1TDO2ALDH1A1HTTCYP2C19
SCHEMBL1368986 0.78 HTT (0.43) IDO1TDO2ALDH1A1HTTCYP2C19
SCHEMBL3296582 0.78 HTT (0.43) IDO1TDO2ALDH1A1HTTCYP2C19
SCHEMBL5185360 0.78 ALDH1A1 (0.34) IDO1TDO2ALDH1A1CYP2C19CYP2C9
SCHEMBL4896389 0.78 IDO1 (0.41) IDO1TDO2ALDH1A1HTTCYP2C19
SCHEMBL5117680 0.77 IDO1 (0.43) IDO1TDO2ALDH1A1HTTCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754571-B Diamine monomer, intrinsic high-dielectric low-loss polyimide, and preparation method and application thereof 中山大学 2022-07-29 CN disclosed
CN-110475796-B Composition for optical material 三菱瓦斯化学株式会社 2022-02-15 CN disclosed
CN-113754571-A Diamine monomer, intrinsic high-dielectric low-loss polyimide, and preparation method and application thereof 中山大学 2021-12-07 CN disclosed
US-11186673-B2 Composition for use as optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-11-30 US disclosed
CN-110105570-B Polyimide material with high heat resistance and low thermal expansion coefficient and preparation method thereof 四川大学 2021-07-09 CN disclosed
US-20200223975-A1 COMPOSITION FOR USE AS OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-07-16 US disclosed
CN-110105570-A A kind of high-fire resistance, low thermal expansion coefficient polyimide material and preparation method thereof 四川大学 2019-08-09 CN disclosed
US-8470860-B2 Phenyl-sulfamates as aromatase inhibitors STERIX LIMITED (GB) 2013-06-25 US disclosed
EP-1966166-B1 1,2,4-TRIAZOL-l-YL BISPHENYL DERIVATIVES FOR USE IN THE TREATMENT OF ENDOCRINE-DEPENDENT TUMOURS STERIX LTD (GB) 2013-01-23 EP disclosed
US-8093279-B2 Compound STERIX LIMITED (GB) 2012-01-10 US disclosed
US-5659005-A Rigid-rod polymers MAXDEM INCORPORATED (US) 1997-08-19 US disclosed
US-5565543-A Rigid-rod polymers MAXDEM INCORPORATED (US) 1996-10-15 US disclosed
US-5227457-A Rigid-rod polymers MAXDEM INCORPORATED (US) 1993-07-13 US disclosed
EP-0489085-A4 RIGID-ROD POLYMERS MAXDEM INC (US) 1992-08-05 EP disclosed
EP-0489085-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1992-06-10 EP disclosed
EP-0401296-A4 RIGID-ROD POLYMERS MAXDEM INC (US) 1992-03-18 EP disclosed
WO-1991002764-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1991-03-07 WO disclosed
EP-0401296-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1990-12-12 EP disclosed
EP-0343560-A2 Isoindoline derivative WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1989-11-29 EP disclosed
WO-1989007617-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1989-08-24 WO disclosed