Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16681203 | 0.89 | NOS3 (0.52) | NOS3NOS2NOS1ABL1MAP4K4 | |
| SCHEMBL30522572 | 0.81 | UHRF1 (0.45) | NOS3NOS2NOS1ABL1MAP4K4 | |
| SCHEMBL17805365 | 0.81 | NOS3 (0.47) | NOS3NOS2NOS1ABL1MAP4K4 | |
| SCHEMBL11254473 | 0.81 | UHRF1 (0.45) | NOS3NOS2NOS1ABL1MAP4K4 | |
| SCHEMBL17805344 | 0.79 | GAA (0.48) | NOS3NOS2NOS1ABL1MAP4K4 | |
| SCHEMBL11373076 | 0.78 | CYP3A4 (0.50) | ABL1PIK3CDUHRF1KDM4EALDH1A1 | |
| SCHEMBL3813235 | 0.78 | NOS3 (0.52) | NOS3NOS2NOS1ABL1MAP4K4 | |
| SCHEMBL4504756 | 0.77 | ABL1 (0.68) | ABL1TDO2FEN1EIF2AK3 | |
| SCHEMBL11065380 | 0.77 | PIK3CD (0.57) | NOS3NOS2MAP4K4PIK3CDMKNK1 | |
| SCHEMBL4495649 | 0.76 | MAP4K4 (0.54) | NOS3NOS2ABL1MAP4K4PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568676-A | IL-17A modulators | 赛诺菲 | 2023-08-08 | — | — | CN | disclosed |
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |