Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17949105 | 0.83 | MAPT (0.42) | MAPTESR2ADORA1NR1H2PARP1 | |
| SCHEMBL28477398 | 0.82 | CNR2 (0.32) | CNR2 | |
| SCHEMBL23632994 | 0.81 | MAPT (0.43) | MAPTESR2ADORA1NR1H2PARP1 | |
| SCHEMBL28881468 | 0.81 | MAPT (0.46) | MAPTESR2ADORA1NR1H2PARP1 | |
| SCHEMBL29191201 | 0.79 | ADORA1 (0.46) | MAPTESR2ADORA1NR1H2PARP1 | |
| SCHEMBL20323953 | 0.78 | PARP1 (0.41) | MAPTESR2ADORA1NR1H2PARP1 | |
| SCHEMBL22675497 | 0.78 | ADORA1 (0.46) | MAPTESR2ADORA1NR1H2PARP1 | |
| SCHEMBL5646141 | 0.78 | DPP4 (0.47) | MAPTESR2ADORA1NR1H2PARP1 | |
| SCHEMBL19713029 | 0.77 | NR1H2 (0.44) | MAPTESR2ADORA1NR1H2PARP1 | |
| SCHEMBL30522679 | 0.74 | PARP1 (0.37) | MAPTESR2NR1H2PARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925367-B | Fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-07 | — | — | CN | disclosed |