Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30522697 | 0.82 | MAPT (0.40) | CNR2 | |
| SCHEMBL28758427 | 0.78 | CNR2 (0.35) | CNR2P2RX7DPP4DPP8DPP7 | |
| SCHEMBL28895623 | 0.77 | PDCD1 (0.36) | CNR2P2RX7DPP4DPP8DPP7 | |
| SCHEMBL23244377 | 0.74 | CNR2 (0.49) | CNR2P2RX7DPP4DPP8DPP7 | |
| SCHEMBL23850214 | 0.67 | P2RX7 (0.47) | CNR2P2RX7DPP4DPP8DPP7 | |
| SCHEMBL28579456 | 0.67 | GRM5 (0.40) | CNR2GRM5 | |
| SCHEMBL23374970 | 0.66 | CCR5 (0.42) | P2RX7DPP4DPP8DPP7DPP9 | |
| SCHEMBL10325665 | 0.66 | GRM5 (0.44) | P2RX7PDK2GRM5 | |
| SCHEMBL19638123 | 0.65 | CNR2 (0.38) | CNR2P2RX7PDK2 | |
| SCHEMBL20460745 | 0.63 | CCR5 (0.44) | CNR2P2RX7DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925367-B | Fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-111925367-A | Fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2020-11-13 | — | — | CN | disclosed |