SCHEMBL30522909

C[C@@H]1CN(C(=O)OC(C)(C)C)[C@@H](c2ccc(Br)cc2)CN1.C[C@@H]1CN(C(=O)OC(C)(C)C)[C@@H](c2ccc(Br)cc2)CN1C(=O)C1(C)CC1

nearest known ligand 0.40

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	NR1H2	P55055	3/20	0.40

▸	NR1H3	Q13133	3/20	0.40

▸	RORC	P51449	2/20	0.39

▸	FPR2	P25090	5/20	0.34

▸	FPR3	P25089	4/20	0.34

▸	XIAP	P98170	3/20	0.31

▸	BIRC2	Q13490	3/20	0.31

▸	SETD7	Q8WTS6	1/20	0.31

▸	USP30	Q70CQ3	1/20	0.31

▸	HSD11B1	P28845	1/20	0.31

▸	GPR119	Q8TDV5	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25328285	0.92	NR1H2 (0.46)	NR1H2NR1H3RORCFPR2FPR3
SCHEMBL25328288	0.92	NR1H2 (0.46)	NR1H2NR1H3RORCFPR2FPR3
SCHEMBL30522902	0.91	RORC (0.36)	NR1H2NR1H3RORCGPR119
SCHEMBL30522976	0.89	NR1H2 (0.39)	NR1H2NR1H3RORCFPR2FPR3
SCHEMBL25326018	0.86	NR1H2 (0.47)	NR1H2NR1H3RORCFPR2FPR3
SCHEMBL25326015	0.86	NR1H2 (0.47)	NR1H2NR1H3RORCFPR2FPR3
SCHEMBL30523044	0.85	NR1H2 (0.41)	NR1H2NR1H3RORCFPR2FPR3
SCHEMBL30522972	0.82	NR1H2 (0.47)	NR1H2NR1H3RORCFPR2FPR3
SCHEMBL25326809	0.81	RORC (0.41)	NR1H2NR1H3RORCGPR119
SCHEMBL25327901	0.81	RORC (0.41)	NR1H2NR1H3RORCGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4469445-A1	COMPOUNDS AND METHODS OF USE	Tango Therapeutics, Inc. (US)	2024-12-04	—	—	EP	disclosed