Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.35 |
| ▸ | BCR | P11274 | 5/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 9/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523353 | 0.90 | PDE1B (0.35) | PDE1BPDE2ACHRM4NOS1 | |
| SCHEMBL30523331 | 0.88 | ABL1 (0.36) | ABL1BCRPDE1BPDE2ACHRM4 | |
| SCHEMBL29921607 | 0.80 | ABL1 (0.37) | ABL1BCR | |
| SCHEMBL29921410 | 0.79 | ABL1 (0.59) | ABL1BCR | |
| SCHEMBL29921666 | 0.79 | ABL1 (0.45) | ABL1BCR | |
| SCHEMBL29921623 | 0.78 | ABL1 (0.48) | ABL1BCR | |
| SCHEMBL29921831 | 0.78 | — | — | |
| SCHEMBL29921918 | 0.78 | ABL1 (0.51) | ABL1BCR | |
| SCHEMBL30523334 | 0.74 | BMPR1B (0.42) | PDE1BPDE2A | |
| SCHEMBL30523330 | 0.71 | PDE2A (0.39) | PDE1BPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761801-A | Heterocyclic compounds having protein kinase inhibitory activity, pharmaceutical compositions containing the same, and methods of preparing and using the same | 四川科伦博泰生物医药股份有限公司 | 2023-09-15 | — | — | CN | disclosed |