Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16146845 | 1.00 | LMNA (0.67) | LMNAALOX15HTTCDK1PDE4A | |
| SCHEMBL30523372 | 0.85 | CDK1 (0.49) | LMNAALOX15HTTCDK1PDE4A | |
| SCHEMBL16146147 | 0.85 | CDK1 (0.49) | LMNAALOX15HTTCDK1PDE4A | |
| SCHEMBL30523425 | 0.85 | LMNA (0.67) | LMNAALOX15HTTCDK1PDE4A | |
| SCHEMBL16146479 | 0.85 | CDK1 (0.49) | LMNAALOX15HTTCDK1PDE4A | |
| SCHEMBL16146196 | 0.85 | CDK1 (0.69) | LMNAALOX15HTTCDK1PDE4A | |
| SCHEMBL30523429 | 0.85 | CDK1 (0.69) | LMNAALOX15HTTCDK1PDE4A | |
| SCHEMBL16145930 | 0.85 | LMNA (0.67) | LMNAALOX15HTTCDK1PDE4A | |
| SCHEMBL16145743 | 0.82 | LMNA (0.48) | LMNAALOX15HTTCDK1PDE4A | |
| SCHEMBL30523377 | 0.82 | LMNA (0.48) | LMNAALOX15HTTCDK1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116492347-A | Compound for activating AMPK and application thereof | 华安医学股份有限公司 | 2023-07-28 | — | — | CN | disclosed |