Sugi Predict

Sugi Predict / Compounds / SCHEMBL305237

SCHEMBL305237

SCHEMBL305237

COC(=O)c1ccccc1C(=O)Cl

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.61
▸ LMNA P02545 2/20 0.61
▸ ALDH1A1 P00352 3/20 0.59
▸ HSD17B10 Q99714 2/20 0.59
▸ CFTR P13569 1/20 0.59
▸ KDM4E B2RXH2 2/20 0.57
▸ POLB P06746 2/20 0.57
▸ ATM Q13315 1/20 0.57
▸ SLC6A3 Q01959 4/20 0.53
▸ SLC6A4 P31645 2/20 0.53
▸ ALOX15 P16050 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ CA1 P00915 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ CA5A P35218 1/20 0.52
▸ CA9 Q16790 1/20 0.52
▸ MAPT P10636 1/20 0.52
▸ MYC P01106 1/20 0.50
▸ GLA P06280 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethyl Phthalate SCHEMBL29500970 0.89 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL790124 0.89 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL34630 0.89 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL29669976 0.89 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
SCHEMBL28747977 0.86 TSHR (0.57) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL28376050 0.86 TSHR (0.71) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL30278536 0.86 TSHR (0.71) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL28064028 0.86 TSHR (0.71) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL10602130 0.86 TSHR (0.71) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL28144606 0.86 TSHR (0.71) TSHRLMNAALDH1A1HSD17B10CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110683974-B Thioether compound, synthesis method thereof and application thereof in polypeptide cyclization 厦门大学 2020-07-31 — — CN claimed
CN-110683974-A Thioether compound, synthesis method thereof and application thereof in polypeptide cyclization 厦门大学 2020-01-14 — — CN claimed
CN-104098589-A 4- [6- (methylthio) benzo [1,2-d:5,4-d' ] di [1,3] oxazole-2-yl ] benzoic acid and preparation method thereof UNIV NANTONG 2014-10-15 — — CN claimed
CN-1326831-C 4-amino-6-nitro resorcin hydrochloride, and its preparation and use UNIV ZHEJIANG TECHNOLOGY (CN) 2007-07-18 — — CN claimed
CN-1275950-C AB type poly(p-phenyl) benzdioxan monomer and its preparation and use UNIV ZHEJIANG POLYTECHNIC (CN) 2006-09-20 — — CN claimed
CN-1644578-A AB type poly(p-phenyl) benzdioxan monomer and its preparation and use UNIV ZHEJIANG POLYTECHNIC (CN) 2005-07-27 — — CN claimed
EP-0951466-A2 CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS Elan Pharmaceuticals, Inc. (US) 1999-10-27 — — EP claimed
WO-1998028268-A2 CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS ELAN PHARMACEUTICALS, INC. (US) 1998-07-02 — — WO claimed
US-5247009-A Reacted with an imine and an acid halide, tires NIPPON ZEON CO., LTD. (JP) 1993-09-21 — — US claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 — — WO claimed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 — — US claimed
US-4677153-A REACTING WITH AN ACYL HALIDE AND NIPPON ZEON CO., LTD. (JP) 1987-06-30 — — US claimed
WO-2025137158-A1 DERIVATIVES OF ([1,2,4]TRIAZOLO[5,1-A]ISOQUINOLINE-5-CARBONYL)GLYCINATE AS PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE AKEBIA THERAPEUTICS, INC. (US) 2025-06-26 — — WO disclosed
CN-113527680-B Polymer, photosensitive resin composition, pattern forming method, cured film, and electronic component 信越化学工业株式会社 2023-04-28 — — CN disclosed
EP-3896521-B1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD, METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHINETSU CHEMICAL CO (JP) 2022-12-14 — — EP disclosed
US-11433061-B2 Heteroaryl sulfonamides and CCR2/CCR9 CHEMOCENTRYX, INC. (US) 2022-09-06 — — US disclosed
US-4017510-A ENANTIOMORPHS AMERICAN CYANAMID COMPANY (US) 1977-04-12 — — US disclosed
US-4016170-A TRANQUILIZERS, SLEEP INDUCERS SANDOZ, INC. (US) 1977-04-05 — — US disclosed
US-4009196-A HYPOTENSIVE AGENTS, BRONCHODILATORS, PROSTAGLANDIN ANALOGS TEIJIN LIMITED (JA) 1977-02-22 — — US disclosed
US-4000275-A BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES ELI LILLY AND COMPANY (US) 1976-12-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11433061-B2 Heteroaryl sulfonamides and CCR2/CCR9 CCR2, CCR9, CCR1 TSHR 1094/4885LMNA 4645/4885ALDH1A1 2834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.