Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.61 |
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | DRD3 | P35462 | 3/20 | 0.60 |
| ▸ | DRD1 | P21728 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 2/20 | 0.60 |
| ▸ | DRD5 | P21918 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 2/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31478053 | 0.80 | DRD2 (0.58) | DRD2HTR1ADRD3DRD1DRD4 | |
| SCHEMBL31478041 | 0.80 | DRD2 (0.60) | DRD2HTR1ADRD3DRD1DRD4 | |
| SCHEMBL30524212 | 0.78 | DRD2 (0.80) | DRD2HTR1ADRD3DRD1DRD4 | |
| SCHEMBL30524202 | 0.77 | DRD2 (0.95) | DRD2HTR1ADRD3DRD1DRD4 | |
| SCHEMBL25331060 | 0.77 | DRD2 (0.50) | DRD2HTR1ADRD3DRD1DRD4 | |
| SCHEMBL31478018 | 0.77 | DRD2 (0.50) | DRD2HTR1ADRD3DRD1DRD4 | |
| SCHEMBL31478050 | 0.77 | DRD2 (1.00) | DRD2HTR1ADRD3DRD1DRD4 | |
| SCHEMBL31478045 | 0.77 | DRD2 (1.00) | DRD2HTR1ADRD3DRD1DRD4 | |
| SCHEMBL25330929 | 0.77 | DRD2 (1.00) | DRD2HTR1ADRD3DRD1DRD4 | |
| SCHEMBL29043054 | 0.77 | DRD2 (1.00) | DRD2HTR1ADRD3DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143393-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海科技大学 | 2023-08-03 | — | — | WO | disclosed |