Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 3/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.67 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.63 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | KIT | P10721 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468934 | 0.88 | FGFR2 (0.71) | PDGFRAPDGFRBFGFR2KDRKIT | |
| SCHEMBL7486400 | 0.84 | FGFR2 (0.84) | PDGFRAPDGFRBFGFR2KDREGFR | |
| SCHEMBL12444104 | 0.82 | PDGFRA (0.76) | PDGFRAPDGFRBFGFR2KDREGFR | |
| SCHEMBL167396 | 0.81 | PDGFRA (0.74) | PDGFRAPDGFRBFGFR2KDREGFR | |
| SCHEMBL4470477 | 0.81 | PDGFRA (0.74) | PDGFRAPDGFRBFGFR2KDR | |
| SCHEMBL7484470 | 0.81 | PDGFRA (0.74) | PDGFRAPDGFRBFGFR2KDREGFR | |
| SCHEMBL16083535 | 0.81 | PDGFRA (0.74) | PDGFRAPDGFRBFGFR2KDREGFR | |
| SCHEMBL3921792 | 0.81 | MET (0.53) | PDGFRAPDGFRBFGFR2KDR | |
| SCHEMBL17117826 | 0.80 | FGFR2 (0.78) | PDGFRAPDGFRBFGFR2KDREGFR | |
| SCHEMBL925876 | 0.80 | PDGFRB (1.00) | PDGFRAPDGFRBFGFR2KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12227511-B2 | Bicyclic compounds as kinase modulators, methods and uses thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2025-02-18 | — | — | US | disclosed |
| US-20230391789-A1 | BICYCLIC COMPOUNDS AS KINASE MODULATORS, METHODS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-12-07 | — | — | US | disclosed |
| US-11702425-B2 | Bicyclic compounds as kinase modulators, methods and uses thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702425-B2 | Bicyclic compounds as kinase modulators, methods and uses thereof | HCCS, PRKAA1, PRKAA2 | PDGFRA 1331/4885PDGFRB 1041/4885FGFR2 1077/4885 |
| US-20230391789-A1 | BICYCLIC COMPOUNDS AS KINASE MODULATORS, METHODS AND USES THEREOF | HCCS, PRKAA1, PRKAA2 | PDGFRA 1331/4885PDGFRB 1041/4885FGFR2 1077/4885 |
| US-12227511-B2 | Bicyclic compounds as kinase modulators, methods and uses thereof | HCCS, PRKAA1, PRKAA2 | PDGFRA 1331/4885PDGFRB 1041/4885FGFR2 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.