SCHEMBL30528008

SCHEMBL30528008

O=C(O)C(F)(F)c1cncc(Cl)n1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 3/20 0.36
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
GRM5 P41594 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
NTRK1 P04629 1/20 0.32
CSF1R P07333 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25259419 1.00 CDK2 (0.36) CDK2CYP11B1CYP11B2GRM5HCAR2
SCHEMBL30527993 0.85 P2RX7 (0.32) HCAR2
SCHEMBL25299818 0.85 P2RX7 (0.32) HCAR2
Trifluoroacetic Acid SCHEMBL1642640 0.80 CDK2 (0.41) CDK2CYP11B1CYP11B2GRM5HCAR2
SCHEMBL30980583 0.80 CSF1R (0.35) CDK2CYP11B1CYP11B2GRM5NTRK1
SCHEMBL1578440 0.76 CDK2 (0.44) CDK2CYP11B1CYP11B2NTRK1CYP3A4
SCHEMBL31261776 0.76 CDK2 (0.44) CDK2CYP11B1CYP11B2NTRK1CYP3A4
SCHEMBL11395905 0.74 TSHR (0.57) GRM5CYP3A4TSHR
SCHEMBL16778251 0.73 CDK2 (0.32) CDK2GRM5
SCHEMBL20773921 0.72 CDK2 (0.41) CDK2CYP11B1CYP11B2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118647270-A Novel derivatives of non-coding amino acids and their use as herbicides 福提费斯特有限公司 2024-09-13 CN claimed
CN-118647270-A Novel derivatives of non-coding amino acids and their use as herbicides 福提费斯特有限公司 2024-09-13 CN disclosed
WO-2023131951-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2023-07-13 WO disclosed