Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28581650 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL30528214 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28588152 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL7257801 | 0.79 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL30532067 | 0.79 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28587261 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28577476 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28584206 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL28579437 | 0.77 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL10621447 | 0.76 | TOP1 (0.45) | KDM4EALDH1A1HPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824396-B | Acrylic ketone derivative of N-acetyl lomefloxacin and preparation method and application thereof | 河南大学 | 2023-08-11 | — | — | CN | disclosed |