⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29578164 | 1.00 | — | — | |
| SCHEMBL3674005 | 0.84 | CHEK1 (0.44) | — | |
| SCHEMBL19011572 | 0.75 | — | — | |
| SCHEMBL2031652 | 0.75 | — | — | |
| SCHEMBL647114 | 0.74 | — | — | |
| SCHEMBL26181459 | 0.73 | PDPK1 (0.47) | — | |
| SCHEMBL16879518 | 0.72 | ATM (0.32) | — | |
| SCHEMBL24942539 | 0.72 | CHEK1 (0.38) | — | |
| SCHEMBL610366 | 0.72 | — | — | |
| SCHEMBL29413210 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 433 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160522-B | Covalent organic framework material and preparation method and application thereof | 吉林中科研伸科技有限公司 | 2023-02-14 | — | — | CN | claimed |
| CN-115160522-A | Covalent organic framework material and preparation method and application thereof | 吉林中科研伸科技有限公司 | 2022-10-11 | — | — | CN | claimed |
| CN-106866699-A | A kind of RTIs of diaryl thienopyrimidines HIV 1 and its preparation method and application | 山东大学 | 2017-06-20 | — | — | CN | claimed |
| US-20050107381-A1 | 6-membered heteroaryl compounds for the treatment of neurodegenerative disorders | PFIZER, INC. | 2005-05-19 | — | — | US | claimed |
| US-20260132140-A1 | IMIDAZOLYL-AMINO-PYRAZINE-CARBONITRILS AS CHK-1 INHIBITORS | BENEVOLENTAI BIO LTD (GB) | 2026-05-14 | — | — | US | disclosed |
| US-12606550-B2 | Methods for synthesis of CHK1 inhibitors | CRT PIONEER FUND LP (GB) | 2026-04-21 | — | — | US | disclosed |
| US-20260090270-A1 | ORGANIC ELECTRONIC ELEMENT AND COMPOUND | TOSOH CORPORATION (JP) | 2026-03-26 | — | — | US | disclosed |
| US-12558345-B2 | CHK1/2 inhibitors for use in the treatment of neuroblastomas and/or soft tissue sarcomas | ELI LILLY AND COMPANY (US) | 2026-02-24 | — | — | US | disclosed |
| US-12527790-B2 | Checkpoint kinase 1 (CHK1) inhibitors and uses thereof | BOUNDLESS BIO, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-20260001870-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2026-01-01 | — | — | US | disclosed |
| US-12492197-B2 | 3,5-disubstituted pyrazole compounds as kinase inhibitors and uses thereof | Impact Therapeutics (Shanghai), Inc (CN) | 2025-12-09 | — | — | US | disclosed |
| US-12448371-B2 | Inhibitor compounds | Cincera Therapeutics Pty Ltd (AU) | 2025-10-21 | — | — | US | disclosed |
| US-20040147748-A1 | 5-Substituted-six-membered heteroaromatic glucokinase activators | CHEN SHAOQING (US) | 2004-07-29 | — | — | US | disclosed |
| WO-2004052869-A1 | 5-SUBSTITUTED-PYRAZINE OR PYRIDINE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-24 | — | — | WO | disclosed |
| CN-1507436-A | Aryl and heteroaryl urea CHK1 inhibitors for use as radiosensitizers and chamosensitizers | — | 2004-06-23 | — | — | CN | disclosed |
| WO-2004014876-A1 | UREA DERIVATIVES AS KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-02-19 | — | — | WO | disclosed |
| US-20040034038-A1 | Urea kinase inhibitors | ABBOTT LABORATORIES | 2004-02-19 | — | — | US | disclosed |
| EP-1379510-A1 | ARYL AND HETEROARYL UREA CHK1 INHIBITORS FOR USE AS RADIOSENSITIZERS AND CHAMOSENSITIZERS | ICOS CORPORATION (US) | 2004-01-14 | — | — | EP | disclosed |
| US-20030069284-A1 | Compounds useful for inhibiting Chk1 | ICOS CORPORATION (A WASHINGTON CORPORATION) | 2003-04-10 | — | — | US | disclosed |
| WO-2002070494-A1 | ARYL AND HETEROARYL UREA CHK1 INHIBITORS FOR USE AS RADIOSENSITIZERS AND CHAMOSENSITIZERS | ICOS CORPORATION (US) | 2002-09-12 | — | — | WO | disclosed |