SCHEMBL610366

SCHEMBL610366

N#Cc1cnc(Cl)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29413210 1.00
SCHEMBL3674005 0.86 CHEK1 (0.44)
SCHEMBL2013423 0.77 PIK3CD (0.42)
SCHEMBL933680 0.76
SCHEMBL24942539 0.74 CHEK1 (0.38)
SCHEMBL9991127 0.74
SCHEMBL30939702 0.74
SCHEMBL2011764 0.73 PIK3CD (0.52)
SCHEMBL21663747 0.72
SCHEMBL305290 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080069-A Phospholipid compounds and uses thereof 2026-05-26 CN disclosed
EP-3898646-B1 3.ALPHA.-HYDROXY-17.BETA.-AMIDE NEUROACTIVE STEROIDS AND COMPOSITIONS THEREOF SAGE THERAPEUTICS LLC (US) 2026-02-18 EP disclosed
US-20260035375-A1 TREM2 MODULATORS MUNA THERAPEUTICS APS (DK) 2026-02-05 US disclosed
US-12534451-B2 Small molecule modulators of PanK ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2026-01-27 US disclosed
US-20260022109-A1 5-HETEROARYL-1H-PYRAZOL-3-AMINE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2026-01-22 US disclosed
US-12527790-B2 Checkpoint kinase 1 (CHK1) inhibitors and uses thereof BOUNDLESS BIO, INC. (US) 2026-01-20 US disclosed
US-20250388542-A1 ANALOGUES OF PENTAMIDINE AND USES THEREFOR AURANSA INC. (US) 2025-12-25 US disclosed
US-12492197-B2 3,5-disubstituted pyrazole compounds as kinase inhibitors and uses thereof Impact Therapeutics (Shanghai), Inc (CN) 2025-12-09 US disclosed
US-20250352541-A1 THERAPEUTIC FOR CANCER REFRACTORY TO IMMUNE CHECKPOINT INHIBITOR Sumitomo Pharma Co., Ltd. (JP) 2025-11-20 US disclosed
US-12473314-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2025-11-18 US disclosed
CN-1305852-C Diaryl ethers as opioid receptor antagonists LILLY CO ELI (US) 2007-03-21 CN disclosed
US-20060217372-A1 Diaryl ethers as opioid receptor antagonist ELI LILLY AND COMPANY 2006-09-28 US disclosed
CN-1681498-A Diaryl ethers as opioid receptor antagonist LILLY CO ELI (US) 2005-10-12 CN disclosed
EP-1562595-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 2005-08-17 EP disclosed
WO-2004026305-A9 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST LILLY CO ELI (US) 2004-05-13 WO disclosed
WO-2004026305-A1 DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST ELI LILLY AND COMPANY (US) 2004-04-01 WO disclosed
EP-0182111-B1 PROCESS FOR THE PREPARATION OF PERHALOGENATED COMPOUNDS BASF Aktiengesellschaft (DE) 1989-09-20 EP disclosed
EP-0182111-A1 Process for the preparation of perhalogenated compounds BASF Aktiengesellschaft (DE) 1986-05-28 EP disclosed
EP-0003562-B1 PROCESS FOR THE PREPARATION OF HYDROXYPHENYL ETHERS BAYER AG (DE) 1981-07-08 EP disclosed
US-4264769-A BY REACTING A DIHYDROXYBENZENE WITH A HETEROCYCLIC OR PHENYL HALIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-28 US disclosed