SCHEMBL30529025

SCHEMBL30529025

Cc1nc(Cl)ccc1C(C)(C)O

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CASR P41180 1/20 0.31
PGR P06401 1/20 0.31
SSTR4 P31391 1/20 0.31
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1246834 1.00 CHRNB2 (0.32) CHRNB2CHRNA4MEN1KMT2ACASR
SCHEMBL10165008 0.83 CHRNB2 (0.33) CHRNB2CHRNA4
SCHEMBL3509045 0.81 MEN1 (0.32) MEN1KMT2APGR
SCHEMBL25373196 0.79
SCHEMBL3509516 0.78 AR (0.33) MEN1KMT2APGR
SCHEMBL16256879 0.77 CYP11B1 (0.37) CHRNB2CHRNA4KMT2A
SCHEMBL1433388 0.75 KDM4E (0.36)
SCHEMBL3508448 0.75 CD274 (0.37) MEN1KMT2A
SCHEMBL27029963 0.71 MEN1 (0.31) MEN1KMT2A
SCHEMBL16198399 0.71 CCR1 (0.34) MEN1KMT2ACASRPGRSSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111094278-B Diphenyl derivative and use thereof 诺华股份有限公司 2023-07-14 CN disclosed