Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 7/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155560 | 1.00 | CYP2A6 (0.45) | CYP2A6CYP2C9CYP2C19CYP2E1CYP3A4 | |
| SCHEMBL5974952 | 0.91 | SLC5A2 (0.39) | CYP2A6CYP2C9CYP2C19CYP2E1CYP3A4 | |
| SCHEMBL156898 | 0.91 | SLC5A2 (0.41) | CYP2A6CYP2C9CYP2C19CYP2E1CYP3A4 | |
| SCHEMBL18505674 | 0.89 | SLC5A2 (0.43) | CYP2A6CYP2C9CYP2C19CYP2E1CYP3A4 | |
| SCHEMBL155572 | 0.88 | SLC5A2 (0.49) | CYP2A6CYP2C9CYP2C19CYP2E1CYP3A4 | |
| SCHEMBL155881 | 0.88 | SLC5A2 (0.40) | CYP2A6CYP2C9CYP2C19CYP2E1CYP3A4 | |
| SCHEMBL152991 | 0.87 | SLC5A2 (0.39) | CYP2A6CYP2C9CYP2C19CYP2E1CYP3A4 | |
| SCHEMBL29366717 | 0.86 | SLC5A2 (0.54) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL154701 | 0.86 | SLC5A2 (0.54) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL152479 | 0.86 | HDAC6 (0.42) | CYP2A6CYP2C9CYP2C19CYP2E1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111077235-B | Method for determining 2- [ (2-methyl-5-bromophenyl) methyl ] -5- (4-fluorophenyl) thiophene impurity | 重庆医药工业研究院有限责任公司 | 2023-09-08 | — | — | CN | claimed |
| US-11852970-B2 | Material for lithography, production method therefor, composition for lithography, pattern formation method, compound, resin, and method for purifying the compound or the resin | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-12-26 | — | — | US | disclosed |
| CN-111077235-B | Method for determining 2- [ (2-methyl-5-bromophenyl) methyl ] -5- (4-fluorophenyl) thiophene impurity | 重庆医药工业研究院有限责任公司 | 2023-09-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11852970-B2 | Material for lithography, production method therefor, composition for lithography, pattern formation method, compound, resin, and method for purifying the compound or the resin | SLC39A11, CROCC, TERB1 | CYP2A6 3824/4885CYP2C9 2626/4885CYP2C19 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.