Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 6/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30529877 | 0.91 | CYP2A6 (0.45) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL155560 | 0.91 | CYP2A6 (0.45) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL5974662 | 0.88 | SLC5A2 (0.52) | SLC5A2CYP2C19CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL5974499 | 0.86 | CYP2C19 (0.38) | SLC5A2SLC5A1PRMT6CYP2C19CYP2E1 | |
| SCHEMBL5973843 | 0.85 | LMNA (0.42) | PRMT6DPP4MAPTKDM4EMEN1 | |
| SCHEMBL156898 | 0.83 | SLC5A2 (0.41) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL18505674 | 0.81 | SLC5A2 (0.43) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL155881 | 0.81 | SLC5A2 (0.40) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL155572 | 0.81 | SLC5A2 (0.49) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 | |
| SCHEMBL152991 | 0.80 | SLC5A2 (0.39) | SLC5A2ABCB11ADORA3SLC5A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651658-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER | TANABE SEIYAKU CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005012326-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER | TANABE SEIYAKU CO., LTD. (JP) | 2005-02-10 | — | — | WO | disclosed |