Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.64 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25374968 | 1.00 | SCN8A (0.64) | SCN8ASCN10ARXFP1HTTLRRK2 | |
| SCHEMBL30530093 | 0.90 | SCN8A (0.64) | SCN8ASCN10A | |
| SCHEMBL25373660 | 0.90 | SCN8A (0.64) | SCN8ASCN10A | |
| SCHEMBL25373117 | 0.89 | SCN8A (0.65) | SCN8ASCN10A | |
| SCHEMBL25375203 | 0.88 | LRRK2 (0.68) | SCN8ASCN10ALRRK2 | |
| SCHEMBL31606710 | 0.88 | SCN8A (0.68) | SCN8ASCN10ARXFP1LRRK2 | |
| SCHEMBL30530087 | 0.88 | LRRK2 (0.68) | SCN8ASCN10ALRRK2 | |
| SCHEMBL25375071 | 0.88 | SCN8A (0.63) | SCN8ASCN10A | |
| SCHEMBL25375406 | 0.88 | SCN8A (0.68) | SCN8ASCN10ARXFP1LRRK2 | |
| SCHEMBL30530067 | 0.88 | SCN8A (0.63) | SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655497-B | Amidine derivative compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2025-06-03 | — | — | CN | disclosed |
| CN-116655497-A | Amidine derivative compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-08-29 | — | — | CN | disclosed |