Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.68 |
| ▸ | SCN8A | Q9UQD0 | 7/20 | 0.65 |
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25375203 | 1.00 | LRRK2 (0.68) | LRRK2SCN8ASCN10A | |
| SCHEMBL30530055 | 0.94 | SCN10A (0.66) | LRRK2SCN8ASCN10A | |
| SCHEMBL25374322 | 0.94 | SCN10A (0.66) | LRRK2SCN8ASCN10A | |
| SCHEMBL30530074 | 0.88 | SCN8A (0.64) | LRRK2SCN8ASCN10A | |
| SCHEMBL25374968 | 0.88 | SCN8A (0.64) | LRRK2SCN8ASCN10A | |
| SCHEMBL25373660 | 0.87 | SCN8A (0.64) | SCN8ASCN10A | |
| SCHEMBL30530093 | 0.87 | SCN8A (0.64) | SCN8ASCN10A | |
| SCHEMBL24518359 | 0.85 | SCN10A (0.65) | SCN8ASCN10A | |
| SCHEMBL29571746 | 0.85 | SCN10A (0.65) | SCN8ASCN10A | |
| SCHEMBL25373555 | 0.85 | SCN8A (0.60) | LRRK2SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655497-B | Amidine derivative compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2025-06-03 | — | — | CN | disclosed |
| CN-116655497-A | Amidine derivative compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-08-29 | — | — | CN | disclosed |