Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | WDR5 | P61964 | 6/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20190805 | 1.00 | RAB9A (0.49) | RAB9AMCHR1HTR2CWDR5AURKA | |
| SCHEMBL21799082 | 0.94 | RAB9A (0.47) | RAB9AMCHR1HTR2CWDR5AURKA | |
| SCHEMBL30114860 | 0.94 | RAB9A (0.47) | RAB9AMCHR1HTR2CWDR5AURKA | |
| SCHEMBL20188209 | 0.92 | RAB9A (0.51) | RAB9AMCHR1HTR2CAURKACDK1 | |
| SCHEMBL30114859 | 0.92 | RAB9A (0.51) | RAB9AMCHR1HTR2CAURKACDK1 | |
| SCHEMBL21799136 | 0.91 | ABL1 (0.48) | RAB9AWDR5WNT3A | |
| SCHEMBL30530284 | 0.91 | ABL1 (0.48) | RAB9AWDR5WNT3A | |
| SCHEMBL21799114 | 0.87 | MCHR1 (0.51) | MCHR1HTR2CHDAC1 | |
| SCHEMBL30530295 | 0.87 | MCHR1 (0.51) | MCHR1HTR2CHDAC1 | |
| SCHEMBL20188432 | 0.86 | ABL1 (0.47) | RAB9AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139692-B | Heteroaryl amine compounds for modulating hedgehog pathway and methods of making and using the same | 财团法人生物技术开发中心 | 2023-08-25 | — | — | CN | claimed |
| CN-110139692-B | Heteroaryl amine compounds for modulating hedgehog pathway and methods of making and using the same | 财团法人生物技术开发中心 | 2023-08-25 | — | — | CN | disclosed |