Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21799093 | 1.00 | ABL1 (0.58) | ABL1KCNH2NPC1LMNATP53 | |
| SCHEMBL21799058 | 0.93 | ABL1 (0.54) | ABL1KCNH2NPC1LMNATP53 | |
| SCHEMBL30530300 | 0.93 | ABL1 (0.54) | ABL1KCNH2NPC1LMNATP53 | |
| SCHEMBL30114863 | 0.91 | ABL1 (0.55) | ABL1KCNH2NPC1LMNATP53 | |
| SCHEMBL21799100 | 0.91 | ABL1 (0.55) | ABL1KCNH2NPC1LMNATP53 | |
| SCHEMBL30530291 | 0.90 | RAB9A (0.51) | NPC1LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL20188564 | 0.90 | RAB9A (0.51) | NPC1LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL21799079 | 0.90 | ABL1 (0.51) | ABL1KCNH2RAB9ASCN9A | |
| SCHEMBL20187750 | 0.90 | ABL1 (0.51) | ABL1KCNH2RAB9A | |
| SCHEMBL30114877 | 0.90 | ABL1 (0.51) | ABL1KCNH2RAB9ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139692-B | Heteroaryl amine compounds for modulating hedgehog pathway and methods of making and using the same | 财团法人生物技术开发中心 | 2023-08-25 | — | — | CN | claimed |
| CN-110139692-B | Heteroaryl amine compounds for modulating hedgehog pathway and methods of making and using the same | 财团法人生物技术开发中心 | 2023-08-25 | — | — | CN | disclosed |