SCHEMBL30530754

SCHEMBL30530754

O=C(O)CN1CCc2cc(Oc3ccccc3)ccc2C1=O

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 20/20 0.66
ITGA2B P08514 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25365464 1.00 ITGB3 (0.66) ITGB3ITGA2B
SCHEMBL25365239 0.87 ITGB3 (0.56) ITGB3ITGA2B
SCHEMBL30530761 0.87 ITGB3 (0.56) ITGB3ITGA2B
SCHEMBL30530722 0.85 ITGB3 (0.53) ITGB3ITGA2B
SCHEMBL25363440 0.85 ITGB3 (0.53) ITGB3ITGA2B
SCHEMBL7788827 0.85 ITGB3 (0.69) ITGB3ITGA2B
SCHEMBL7799399 0.81 ITGB3 (0.64) ITGB3ITGA2B
SCHEMBL4880991 0.80 KDM4E (0.55) ITGB3ITGA2B
SCHEMBL31445044 0.80 KDM4E (0.55) ITGB3ITGA2B
SCHEMBL25363677 0.80 TDP1 (0.51) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116437913-A Pharmaceutical compounds for treating complement-mediated disorders 艾其林医药公司 2023-07-14 CN disclosed