Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 5/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445131 | 1.00 | CASP6 (0.45) | CASP6CYP19A1IDO1KDM1ACYP46A1 | |
| Formic Acid SCHEMBL21411987 | 0.91 | CASP6 (0.40) | CASP6CYP19A1IDO1KDM1ACYP46A1 | |
| SCHEMBL27576051 | 0.86 | CASP6 (0.44) | CASP6IDO1CYP46A1ALDH1A1HPGD | |
| SCHEMBL23263132 | 0.85 | CASP6 (0.41) | CASP6CYP19A1IDO1CYP46A1ALDH1A1 | |
| SCHEMBL29889975 | 0.85 | CASP6 (0.41) | CASP6CYP19A1IDO1CYP46A1ALDH1A1 | |
| SCHEMBL10601314 | 0.85 | MAPK9 (0.43) | CASP6CYP46A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1414824 | 0.85 | CASP6 (0.43) | CASP6IDO1CYP46A1ALDH1A1HPGD | |
| SCHEMBL30396238 | 0.78 | CASP6 (0.47) | CASP6CYP46A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL28135246 | 0.78 | RPS6KA3 (0.50) | CASP6BCL2L1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL56776 | 0.77 | KDM4E (0.56) | CYP19A1IDO1KDM1AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601167-A | Compositions of Guanylate Cyclase C (GCC) antigen binding agents and methods of use thereof | 武田药品工业株式会社 | 2023-08-15 | — | — | CN | disclosed |