Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 16/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 16/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30532180 | 0.85 | GRIN1 (0.50) | GRIN1GRIN2BDAOPKMMAPK10 | |
| SCHEMBL17966780 | 0.83 | TP53 (0.53) | GRIN1GRIN2BDAOMAPTPKM | |
| SCHEMBL7499251 | 0.80 | KDM4E (0.60) | DAO | |
| SCHEMBL30532156 | 0.75 | PTGDR2 (0.49) | GRIN1GRIN2BDAO | |
| SCHEMBL29722691 | 0.72 | KDM4E (0.56) | DAOMAPT | |
| SCHEMBL23269038 | 0.72 | ATM (0.74) | GRIN1GRIN2B | |
| SCHEMBL24312042 | 0.71 | DAO (0.58) | DAO | |
| SCHEMBL891521 | 0.69 | DAO (0.55) | DAO | |
| SCHEMBL9981108 | 0.68 | DAO (0.58) | DAO | |
| SCHEMBL6980977 | 0.68 | PKM (0.79) | PKMMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523311-B1 | SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-07 | — | — | EP | disclosed |