Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 7/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | HTR6 | P50406 | 7/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997682 | 1.00 | SIRT6 (0.75) | SIRT6MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL30900326 | 0.87 | SIRT6 (0.67) | SIRT6MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL1527190 | 0.87 | SIRT6 (0.67) | SIRT6MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL170932 | 0.87 | HPGD (0.75) | SIRT6MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL23124217 | 0.86 | SIRT6 (0.58) | SIRT6MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL2910036 | 0.86 | SIRT6 (0.69) | SIRT6MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL520215 | 0.86 | SIRT6 (0.69) | SIRT6MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL77148 | 0.86 | SIRT6 (1.00) | SIRT6MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL6978950 | 0.86 | SIRT6 (0.65) | SIRT6MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL24267633 | 0.86 | SIRT6 (0.69) | SIRT6MAPTMAPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606888-B | Pyrrole derivative and preparation method and application thereof | 中国药科大学 | 2023-08-18 | — | — | CN | disclosed |