Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 14/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30175294 | 0.83 | RET (0.43) | RETDRD2DRD1DRD4HTR2A | |
| SCHEMBL30175367 | 0.82 | RET (0.48) | RET | |
| SCHEMBL30175349 | 0.81 | CYP11B1 (0.41) | RETDRD2DRD1DRD4HTR2A | |
| SCHEMBL30175296 | 0.81 | RET (0.45) | RET | |
| SCHEMBL29566683 | 0.80 | RET (0.45) | RET | |
| Hydrochloric Acid SCHEMBL28993707 | 0.79 | RET (0.44) | RET | |
| SCHEMBL30175335 | 0.78 | RET (0.37) | RETDRD2DRD1DRD4HTR2A | |
| SCHEMBL25252185 | 0.78 | CDK2 (0.36) | RETDRD2DRD1DRD4HTR2A | |
| SCHEMBL30175370 | 0.78 | CDK2 (0.36) | RETDRD2DRD1DRD4HTR2A | |
| SCHEMBL31458875 | 0.78 | RET (0.47) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444515-A | Di-ring derivative-containing inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-18 | — | — | CN | disclosed |