Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24478113 | 1.00 | CCR8 (0.49) | CCR8DRD2DRD4OPRM1KDM4E | |
| SCHEMBL30534082 | 0.92 | DRD2 (0.47) | DRD2DRD4OPRM1 | |
| SCHEMBL26351132 | 0.92 | DRD2 (0.47) | DRD2DRD4OPRM1 | |
| SCHEMBL30534091 | 0.89 | DRD2 (0.55) | DRD2DRD4OPRM1 | |
| SCHEMBL24478177 | 0.89 | DRD2 (0.55) | DRD2DRD4OPRM1 | |
| SCHEMBL24478123 | 0.87 | DRD2 (0.52) | DRD2DRD4OPRM1KDM4EALDH1A1 | |
| SCHEMBL29712635 | 0.86 | OPRL1 (0.52) | DRD2DRD4OPRM1ALDH1A1 | |
| SCHEMBL26351139 | 0.86 | OPRL1 (0.52) | DRD2DRD4OPRM1ALDH1A1 | |
| SCHEMBL30585918 | 0.85 | DRD2 (0.53) | DRD2DRD4OPRM1KDM4EALDH1A1 | |
| SCHEMBL26351102 | 0.85 | DRD2 (0.53) | DRD2DRD4OPRM1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249489-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | Lg Chem, Ltd. (KR) | 2023-09-27 | — | — | EP | claimed |
| CN-116615199-A | Heterocyclic compounds as diacylglycerol kinase inhibitors and uses thereof | 株式会社LG化学 | 2023-08-18 | — | — | CN | claimed |
| EP-4249489-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | Lg Chem, Ltd. (KR) | 2023-09-27 | — | — | EP | disclosed |
| CN-116615199-A | Heterocyclic compounds as diacylglycerol kinase inhibitors and uses thereof | 株式会社LG化学 | 2023-08-18 | — | — | CN | disclosed |