⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576635 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL29955353 | 0.98 | UHRF1 (0.48) | — | |
| SCHEMBL9689167 | 0.87 | UHRF1 (0.39) | — | |
| SCHEMBL6405453 | 0.86 | CYP2A6 (0.43) | — | |
| SCHEMBL3225089 | 0.86 | CYP2A6 (0.43) | — | |
| SCHEMBL3465817 | 0.80 | UHRF1 (0.48) | — | |
| SCHEMBL20860597 | 0.79 | XDH (0.44) | — | |
| SCHEMBL14072614 | 0.79 | BRD4 (0.49) | — | |
| SCHEMBL6630611 | 0.79 | — | — | |
| SCHEMBL14676678 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264909-A | Andrographolide derivative and preparation method and application thereof | 沈阳药科大学 | 2021-08-17 | — | — | CN | claimed |
| CN-111153910-B | Elephantopus scaber seed lactone derivative and preparation method and application thereof | 沈阳药科大学 | 2021-07-30 | — | — | CN | claimed |
| WO-2021013419-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | HENKEL AG & CO. KGAA (DE) | 2021-01-28 | — | — | WO | claimed |
| US-10131640-B2 | Anti-inflammatory agents | RESVERLOGIX CORP. (CA) | 2018-11-20 | — | — | US | claimed |
| CN-105859639-A | NOVEL ANTI-INFLAMMATORY AGENTS | 雷斯韦洛吉克斯公司 | 2016-08-17 | — | — | CN | claimed |
| CN-104016898-B | 3,4-disubstituted pyrroles compounds and its preparation method and application | 上海交通大学 | 2016-07-06 | — | — | CN | claimed |
| US-20160137613-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2016-05-19 | — | — | US | claimed |
| CN-105367558-A | Andrographolide derivative and preparation method and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2016-03-02 | — | — | CN | claimed |
| WO-2015194981-A1 | NEW METALLOLIGAND, A METAL-ORGANIC FRAMEWORK (MOF) COMPRISING THEREOF AND A METHOD FOR ITS PREPARATION | Uniwersytet Jagielloński (PL) | 2015-12-23 | — | — | WO | claimed |
| CN-104370880-A | Protease inhibitor and preparing method and use thereof | HAN BING | 2015-02-25 | — | — | CN | claimed |
| CN-104370882-A | Intraocular tension reducing compound and preparation method and use thereof | HAN BING | 2015-02-25 | — | — | CN | claimed |
| CN-104370881-A | Neuroprotective effect compound and preparation method and use thereof | HAN BING | 2015-02-25 | — | — | CN | claimed |
| EP-2797597-A1 | SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | Global Blood Therapeutics, Inc. (US) | 2014-11-05 | — | — | EP | claimed |
| WO-2014145040-A1 | SUBSTITUTED ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2014-09-18 | — | — | WO | claimed |
| US-20130281399-A1 | TREATMENT OF DISEASES BY EPIGENETIC REGULATION | RVX THERAPEUTICS INC. (CA) | 2013-10-24 | — | — | US | claimed |
| WO-2013102145-A1 | SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2013-07-04 | — | — | WO | claimed |
| EP-2408454-A2 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2012-01-25 | — | — | EP | claimed |
| WO-2010106436-A2 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2010-09-23 | — | — | WO | claimed |
| US-20020188122-A1 | Novel compounds | SMITHKLINE BEECHAM CORPORATION | 2002-12-12 | — | — | US | claimed |
| EP-1229035-A1 | Imine intermediates for the preparation of trisubstituted imidazole compounds with multiple therapeutic properties | SMITHKLINE BEECHAM CORPORATION (US) | 2002-08-07 | — | — | EP | claimed |