Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3053578 | 1.00 | ACE (0.43) | ACEKLK5ATMCTSSCTSL | |
| SCHEMBL3045577 | 0.89 | KLK5 (0.42) | ACEKLK5ATMCTSSCTSL | |
| SCHEMBL3045572 | 0.89 | KLK5 (0.42) | ACEKLK5ATMCTSSCTSL | |
| SCHEMBL9657327 | 0.84 | KLK5 (0.47) | ACEKLK5ATMCTSSCTSL | |
| SCHEMBL7362380 | 0.84 | KLK5 (0.47) | ACEKLK5ATMCTSSCTSL | |
| SCHEMBL3046771 | 0.84 | KLK5 (0.51) | ACEKLK5ATMCTSSCTSL | |
| SCHEMBL3053640 | 0.84 | KLK5 (0.51) | ACEKLK5ATMCTSSCTSL | |
| SCHEMBL3046768 | 0.84 | KLK5 (0.51) | ACEKLK5ATMCTSSCTSL | |
| SCHEMBL3053637 | 0.84 | KLK5 (0.51) | ACEKLK5ATMCTSSCTSL | |
| SCHEMBL9658726 | 0.83 | KLK5 (0.49) | ACEKLK5ATMCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691818-B2 | Peptidomimetic inhibitors of retroviral proteases and their use as antivirals | Universita' Degli Studi Di Treiste (IT) | 2010-04-06 | — | — | US | disclosed |
| EP-1768665-B1 | PEPTIDOMIMETIC INHIBITORS OF HIV PROTEASE | UNIV DEGLI STUDI TRIESTE (IT) | 2008-11-05 | — | — | EP | disclosed |
| US-20070207968-A1 | Peptidomimetic Inhibitors Of Retroviral Proteases And Their Use As Antivirals | UNIVERSITA' DEGLI STUDI DI TRIESTE (IT) | 2007-09-06 | — | — | US | disclosed |
| EP-1768665-A1 | PEPTIDOMIMETIC INHIBITORS OF RETROVIRAL PROTEASES AND THEIR USE AS ANTIVIRALS | Universita'Degli Studi di Trieste (IT) | 2007-04-04 | — | — | EP | disclosed |
| WO-2005123067-A1 | PEPTIDOMIMETIC INHIBITORS OF RETROVIRAL PROTEASES AND THEIR USE AS ANTIVIRALS | UNIVERSITA' DEGLI STUDI DI TRIESTE (IT) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207968-A1 | Peptidomimetic Inhibitors Of Retroviral Proteases And Their Use As Antivirals | PREP, PEPD, DNPEP | ACE 41/4885KLK5 3017/4885ATM 3387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.