SCHEMBL30537293

SCHEMBL30537293

COc1ccc(C(F)(F)C(=O)Nc2ccc(F)cc2)cc1OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
ALDH1A1 P00352 2/20 0.51
MET P08581 1/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
MAPT P10636 3/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MAPK1 P28482 2/20 0.46
XBP1 P17861 1/20 0.46
HTT P42858 1/20 0.46
TRPV1 Q8NER1 1/20 0.45
PDE10A Q9Y233 1/20 0.44
IMPDH2 P12268 1/20 0.44
IMPDH1 P20839 1/20 0.44
TP53 P04637 1/20 0.44
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29054806 1.00 CYP1A2 (0.59) CYP1A2CYP2C9CYP2C19ALDH1A1MET
SCHEMBL30537290 0.88 CYP1A2 (0.57) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL29054809 0.88 CYP1A2 (0.57) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL30537294 0.85 ALDH1A1 (0.58) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL29054922 0.85 ALDH1A1 (0.58) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL602651 0.77 GAA (0.55) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL4440336 0.75 CYP1A2 (1.00) CYP1A2CYP2C9CYP2C19ALDH1A1MEN1
SCHEMBL4243486 0.74 RAF1 (0.61) ALDH1A1MEN1KMT2AMAPTNPC1
SCHEMBL14861729 0.73 ALDH1A1 (0.51) ALDH1A1MEN1KMT2AMAPTNPC1
SCHEMBL14093038 0.72 DHODH (0.58) ALDH1A1MEN1KMT2AMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116621726-B Phenyl difluoro amidated aromatic hydrocarbon compound, preparation method and application thereof 上海大学 2025-05-27 CN disclosed
CN-116621726-A Phenyl difluoro amidated aromatic hydrocarbon compound, preparation method and application thereof 上海大学 2023-08-22 CN disclosed