Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25405428 | 1.00 | MEN1 (0.32) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24757043 | 0.94 | AAK1 (0.33) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29813229 | 0.88 | BRAF (0.30) | EGLN2 | |
| SCHEMBL28807303 | 0.88 | BRAF (0.30) | EGLN2 | |
| SCHEMBL23499098 | 0.88 | BRAF (0.31) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29810894 | 0.88 | BRAF (0.31) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30015365 | 0.84 | — | — | |
| SCHEMBL25643118 | 0.82 | AAK1 (0.34) | MEN1KMT2A | |
| SCHEMBL29810903 | 0.81 | BRAF (0.31) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL26967285 | 0.81 | BRAF (0.31) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4489738-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Kumquat Biosciences Inc. (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |