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Sugi Predict / Compounds / Formic Acid

Formic Acid

Formic Acid

SCHEMBL30537906

CNC(=O)c1ccc(-c2cn3c(n2)sc2cc(C(=O)NCCCN4CC5CC4CN5C)ccc23)cc1.O=CO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 1/20 0.58
▸ MAPT P10636 7/20 0.57
▸ TP53 P04637 5/20 0.55
▸ THRB P10828 2/20 0.55
▸ POLB P06746 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ LMNA P02545 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24619571 0.97 SLC2A1 (0.61) SLC2A1MAPTTP53THRBPOLB
SCHEMBL24740812 0.86 MAPT (0.60) SLC2A1MAPTTP53THRBPOLB
SCHEMBL29925296 0.86 MAPT (0.60) SLC2A1MAPTTP53THRBPOLB
Formic Acid SCHEMBL29925647 0.84 LMNA (0.64) MAPTTP53THRBPOLBSMN1; SMN2
Formic Acid SCHEMBL29925480 0.81 MAPT (0.58) SLC2A1MAPTTP53THRBPOLB
SCHEMBL24619911 0.81 SLC2A1 (0.69) SLC2A1MAPTTP53THRBPOLB
SCHEMBL24741002 0.81 MAPT (0.84) SLC2A1MAPTTP53THRBPOLB
SCHEMBL30085964 0.81 MAPT (0.84) SLC2A1MAPTTP53THRBPOLB
SCHEMBL24619803 0.81 LMNA (0.68) MAPTTP53THRBPOLBSMN1; SMN2
SCHEMBL24619222 0.81 MAPT (0.86) SLC2A1MAPTTP53THRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116635028-A Modulators of c-MYC mRNA translation and their use in the treatment of cancer 艾尼莫生物科技公司 2023-08-22 — — CN disclosed
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