Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | CPB1 | P15086 | 2/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19150112 | 0.84 | ALDH1A1 (0.59) | ALDH1A1GAATSHRENPP2ATXN2 | |
| SCHEMBL19149069 | 0.84 | ALDH1A1 (0.59) | ALDH1A1GAATSHRENPP2ATXN2 | |
| SCHEMBL31643889 | 0.84 | ALDH1A1 (0.63) | ALDH1A1GAATSHREPHX1CTSL | |
| SCHEMBL4315139 | 0.84 | ALDH1A1 (0.63) | ALDH1A1GAATSHREPHX1CTSL | |
| SCHEMBL21496920 | 0.83 | ALDH1A1 (0.69) | ALDH1A1GAATSHRENPP2ATXN2 | |
| SCHEMBL16616249 | 0.83 | ALDH1A1 (0.58) | ALDH1A1GAATSHRENPP2ATXN2 | |
| SCHEMBL26602184 | 0.82 | ALDH1A1 (0.56) | ALDH1A1GAATSHRENPP2ATXN2 | |
| SCHEMBL25819454 | 0.81 | ALDH1A1 (0.55) | ALDH1A1GAATSHRENPP2ATXN2 | |
| SCHEMBL16485927 | 0.81 | ALDH1A1 (0.58) | ALDH1A1GAATSHRENPP2ATXN2 | |
| SCHEMBL19150130 | 0.81 | ALDH1A1 (0.58) | ALDH1A1GAATSHRENPP2ATXN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818704-B | Spiro bridged ring compounds, pharmaceutical compositions thereof and uses thereof | 广州市恒诺康医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |