Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ROS1 | P08922 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25348421 | 1.00 | AKR1B1 (0.44) | AKR1B1KLKB1KLK1CNR1EPHX2 | |
| SCHEMBL30539557 | 0.85 | AKR1B1 (0.43) | AKR1B1KLKB1KLK1CNR1EPHX2 | |
| SCHEMBL25348145 | 0.85 | AKR1B1 (0.43) | AKR1B1KLKB1KLK1CNR1EPHX2 | |
| SCHEMBL25990257 | 0.82 | AKR1B1 (0.42) | AKR1B1KLKB1KLK1CNR1EPHX2 | |
| SCHEMBL30539556 | 0.81 | AKR1B1 (0.48) | AKR1B1KLKB1KLK1CNR1EPHX2 | |
| SCHEMBL25346972 | 0.81 | AKR1B1 (0.48) | AKR1B1KLKB1KLK1CNR1EPHX2 | |
| SCHEMBL25990246 | 0.80 | AKR1B1 (0.40) | AKR1B1KLKB1KLK1CNR1EPHX2 | |
| SCHEMBL25981509 | 0.80 | AKR1B1 (0.40) | AKR1B1KLKB1KLK1CNR1EPHX2 | |
| SCHEMBL25990239 | 0.80 | AKR1B1 (0.40) | AKR1B1KLKB1KLK1EPHX2ABCB1 | |
| SCHEMBL25344184 | 0.79 | AKR1B1 (0.39) | AKR1B1KLKB1KLK1EPHX2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479388-A1 | ANTIVIRAL NAPHTHYRIDINONE COMPOUNDS | Gilead Sciences, Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023154905-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-08-17 | — | — | WO | disclosed |