Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30539556 | 1.00 | AKR1B1 (0.48) | AKR1B1ABCB1KLKB1KLK1CNR2 | |
| SCHEMBL30539557 | 0.88 | AKR1B1 (0.43) | AKR1B1ABCB1KLKB1KLK1CNR2 | |
| SCHEMBL25348145 | 0.88 | AKR1B1 (0.43) | AKR1B1ABCB1KLKB1KLK1CNR2 | |
| SCHEMBL30539591 | 0.83 | MAPK8 (0.44) | AKR1B1ABCB1KLKB1KLK1CNR2 | |
| SCHEMBL30539678 | 0.81 | AKR1B1 (0.44) | AKR1B1ABCB1KLKB1KLK1CNR2 | |
| SCHEMBL25348421 | 0.81 | AKR1B1 (0.44) | AKR1B1ABCB1KLKB1KLK1CNR2 | |
| SCHEMBL25984911 | 0.80 | CNR2 (0.37) | AKR1B1ABCB1KLKB1KLK1CNR2 | |
| SCHEMBL25350030 | 0.80 | AKR1B1 (0.39) | AKR1B1ABCB1KLKB1KLK1CNR2 | |
| SCHEMBL30539733 | 0.80 | AKR1B1 (0.39) | AKR1B1ABCB1KLKB1KLK1CNR2 | |
| SCHEMBL25991776 | 0.79 | CNR2 (0.39) | AKR1B1ABCB1KLKB1KLK1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2026-05-07 | — | — | US | disclosed |
| WO-2023154905-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023154905-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | ZC3HAV1, CCR1, CCR6 | AKR1B1 1434/4885ABCB1 2119/4885KLKB1 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.