Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.33 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25364103 | 1.00 | CHRM1 (0.49) | CHRM1CHRM2CHRM3USP2SMN1; SMN2 | |
| SCHEMBL18235300 | 0.85 | CHRM1 (0.60) | CHRM1CHRM2CHRM3USP2SMN1; SMN2 | |
| SCHEMBL30567071 | 0.83 | CHRM2 (0.48) | CHRM1CHRM2CHRM3USP2SMN1; SMN2 | |
| SCHEMBL26064977 | 0.83 | CHRM2 (0.48) | CHRM1CHRM2CHRM3USP2SMN1; SMN2 | |
| SCHEMBL31554879 | 0.82 | CHRM1 (0.45) | CHRM1CHRM2CHRM3USP2SMN1; SMN2 | |
| SCHEMBL30540043 | 0.81 | USP2 (0.59) | USP2SMN1; SMN2RECQLCCR2GPR119 | |
| SCHEMBL25366279 | 0.81 | USP2 (0.59) | USP2SMN1; SMN2RECQLCCR2GPR119 | |
| SCHEMBL30539365 | 0.80 | CHRM2 (0.66) | CHRM1CHRM2CHRM3USP2SMN1; SMN2 | |
| SCHEMBL30539374 | 0.79 | CHRM2 (0.55) | CHRM1CHRM2CHRM3RECQLPREP | |
| SCHEMBL25365341 | 0.78 | HRH3 (0.39) | SMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479384-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023154499-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-17 | — | — | WO | disclosed |