SCHEMBL25366279

SCHEMBL25366279

CC(C)(C)OC(=O)N1CCC2(CC1)CC(N1CCOCC1)C2

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
RECQL P46063 1/20 0.52
GPR119 Q8TDV5 6/20 0.43
EPHX2 P34913 1/20 0.41
NAMPT P43490 2/20 0.40
HRH3 Q9Y5N1 3/20 0.40
CCR2 P41597 1/20 0.39
HPGD P15428 1/20 0.39
SCD5 Q86SK9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30540043 1.00 USP2 (0.59) USP2SMN1; SMN2RECQLGPR119EPHX2
SCHEMBL25365082 0.91 USP2 (0.55) USP2SMN1; SMN2RECQLGPR119EPHX2
SCHEMBL20669397 0.87 HPGD (0.48) USP2SMN1; SMN2RECQLGPR119EPHX2
SCHEMBL20669370 0.86 HPGD (0.50) USP2SMN1; SMN2RECQLGPR119EPHX2
SCHEMBL24746946 0.85 USP2 (0.50) USP2SMN1; SMN2RECQLGPR119EPHX2
SCHEMBL24480361 0.84 GPR119 (0.43) USP2SMN1; SMN2GPR119EPHX2NAMPT
SCHEMBL20669374 0.84 GPR119 (0.43) USP2SMN1; SMN2GPR119EPHX2NAMPT
SCHEMBL26699680 0.84 GPR119 (0.43) USP2SMN1; SMN2RECQLGPR119EPHX2
SCHEMBL31511899 0.83 USP2 (0.51) USP2SMN1; SMN2RECQLGPR119EPHX2
SCHEMBL31511898 0.83 USP2 (0.51) USP2SMN1; SMN2RECQLGPR119EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250152574-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. 2025-05-15 US disclosed
CN-119731156-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-03-28 CN disclosed
EP-4479384-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2024-12-25 EP disclosed
WO-2023154499-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-17 WO disclosed
WO-2023154499-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-08-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250152574-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBPL, EBP, CREBBP USP2 3261/4885SMN1; SMN2 1668/4885RECQL 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.