Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 17/20 | 0.62 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700751 | 0.92 | SMYD3 (0.54) | SMYD3GRM5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26414404 | 0.84 | NPC1 (0.69) | GRM5NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL24359915 | 0.80 | NPC1 (0.71) | SMYD3NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3811649 | 0.80 | SMYD3 (0.68) | SMYD3NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3809790 | 0.80 | NPC1 (0.71) | SMYD3NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL13700747 | 0.79 | NPC1 (0.52) | GRM5NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3812383 | 0.79 | SMYD3 (0.82) | SMYD3NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24512933 | 0.79 | SMYD3 (0.82) | SMYD3NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24360441 | 0.79 | SMYD3 (0.62) | SMYD3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24360439 | 0.79 | SMYD3 (0.62) | SMYD3NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710434-A | Modulators of MAS-related G protein receptor X2 and related products and uses thereof | 伊赛恩特制药公司 | 2023-09-05 | — | — | CN | disclosed |