Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700751 | 0.88 | SMYD3 (0.54) | NPC1RAB9AMAPTKDM4EKMT2A | |
| SCHEMBL13707511 | 0.83 | NPC1 (0.46) | NPC1RAB9AMAPTKDM4EKMT2A | |
| SCHEMBL30540356 | 0.79 | SMYD3 (0.62) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL26414404 | 0.79 | NPC1 (0.69) | NPC1RAB9AKDM4EKMT2AGRM5 | |
| SCHEMBL9888561 | 0.78 | MAPT (0.67) | NPC1RAB9AMAPTKDM4EKMT2A | |
| SCHEMBL12040482 | 0.78 | MAPT (0.67) | NPC1RAB9AMAPTKDM4EKMT2A | |
| SCHEMBL17457477 | 0.75 | HDAC6 (0.72) | NPC1RAB9AMAPTKDM4EKMT2A | |
| SCHEMBL17457476 | 0.75 | HDAC6 (0.72) | NPC1RAB9AMAPTKDM4EKMT2A | |
| SCHEMBL12093588 | 0.75 | RAB9A (0.73) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL25774166 | 0.74 | NPC1 (0.67) | NPC1RAB9AMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2105146-A1 | Nucleic-acid triggered release of molecules | Riken (JP) | 2009-09-30 | — | — | EP | disclosed |
| US-20090227691-A1 | METHOD FOR RELEASING MOLECULE OF INTEREST BASED ON TARGET NUCLEIC ACID SEQUENCE | RIKEN (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090227691-A1 | METHOD FOR RELEASING MOLECULE OF INTEREST BASED ON TARGET NUCLEIC ACID SEQUENCE | RIKEN (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227691-A1 | METHOD FOR RELEASING MOLECULE OF INTEREST BASED ON TARGET NUCLEIC ACID SEQUENCE | DUT, ADAR, RNGTT | NPC1 1539/4885RAB9A 4312/4885MAPT 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.