Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 18/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540646 | 0.84 | MAPK1 (0.34) | EEF2K | |
| SCHEMBL30540577 | 0.78 | EEF2K (0.38) | EEF2KGRM2LMNA | |
| SCHEMBL30540558 | 0.74 | GRM2 (0.37) | GRM2LMNA | |
| SCHEMBL30625623 | 0.73 | EEF2K (0.35) | EEF2KGRM2LMNA | |
| SCHEMBL30625415 | 0.72 | MAPK1 (0.33) | — | |
| SCHEMBL30625588 | 0.70 | EEF2K (0.36) | EEF2K | |
| SCHEMBL30540659 | 0.70 | EEF2K (0.36) | EEF2KLMNA | |
| SCHEMBL30625617 | 0.70 | EEF2K (0.37) | EEF2KGRM2 | |
| SCHEMBL31115335 | 0.69 | ERN1 (0.34) | GRM2LMNA | |
| SCHEMBL30540572 | 0.69 | ERN1 (0.34) | GRM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4476219-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BeiGene, Ltd. (KY) | 2024-12-18 | — | — | EP | disclosed |
| CN-118696043-A | Heterocyclic compounds, compositions thereof and methods of treatment therewith | 百济神州有限公司 | 2024-09-24 | — | — | CN | disclosed |
| WO-2023151642-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151636-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |