Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540529 | 0.88 | RARA (0.33) | PTGS1PTGS2ALOX5 | |
| SCHEMBL25348987 | 0.84 | RARB (0.34) | PTGS1PTGS2ALOX5 | |
| SCHEMBL30625508 | 0.74 | CD38 (0.33) | GRM2PTGS1PTGS2ALOX5 | |
| SCHEMBL30540451 | 0.74 | EEF2K (0.42) | GRM2LMNA | |
| SCHEMBL25350416 | 0.73 | RARB (0.34) | PTGS1PTGS2ALOX5 | |
| SCHEMBL30625612 | 0.72 | CD38 (0.35) | PTGS1PTGS2ALOX5 | |
| SCHEMBL30625520 | 0.72 | RARA (0.36) | — | |
| SCHEMBL30540591 | 0.71 | MAP3K14 (0.39) | GRM2PTGS1PTGS2 | |
| SCHEMBL30540509 | 0.69 | PABPC1 (0.39) | LMNAPTGS1PTGS2 | |
| SCHEMBL30625449 | 0.69 | PTGS1 (0.32) | PTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4476219-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BeiGene, Ltd. (KY) | 2024-12-18 | — | — | EP | disclosed |
| CN-118696043-A | Heterocyclic compounds, compositions thereof and methods of treatment therewith | 百济神州有限公司 | 2024-09-24 | — | — | CN | disclosed |
| WO-2023151642-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023151636-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |