SCHEMBL30540772

SCHEMBL30540772

C[C@@H](Oc1cccc2c1c(I)nn2C1CCCCO1)c1c(Cl)cncc1Cl

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RET P07949 2/20 0.34
CYP4F2 P78329 2/20 0.31
CYP4A11 Q02928 2/20 0.31
DGAT2 Q96PD7 1/20 0.31
ATR Q13535 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31484985 0.89 RET (0.35) RETCYP4F2CYP4A11
SCHEMBL30713525 0.88 RET (0.33) RETCYP4F2CYP4A11ATR
SCHEMBL30540816 0.86 RET (0.34) RETCYP4F2CYP4A11ATR
SCHEMBL31484940 0.85 RET (0.34) RET
SCHEMBL31327358 0.81 CYP4F2 (0.34) RETCYP4F2CYP4A11DGAT2ATR
SCHEMBL31185845 0.81 ATR (0.33) RETCYP4F2CYP4A11ATR
SCHEMBL31361807 0.80 ATR (0.36) RETCYP4F2CYP4A11ATR
SCHEMBL29092373 0.80 CYP4F2 (0.33) RETCYP4F2CYP4A11DGAT2ATR
SCHEMBL29712243 0.80 RET (0.33) RETDGAT2ATR
SCHEMBL27188228 0.80 RET (0.33) RETDGAT2ATR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119731165-A Indazole compounds 泰拉生物科学公司 2025-03-28 CN disclosed
CN-116761798-A Indazoles as kinase inhibitors 泰拉生物科学公司 2023-09-15 CN disclosed