Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540754 | 0.85 | EGFR (0.37) | ATRCYP4F2CYP4A11RET | |
| SCHEMBL15568853 | 0.83 | CYP4F2 (0.39) | ATRCYP4F2CYP4A11RETMAP3K5 | |
| SCHEMBL31484933 | 0.83 | CYP4F2 (0.39) | ATRCYP4F2CYP4A11RETMAP3K5 | |
| SCHEMBL31190804 | 0.81 | CYP4F2 (0.33) | CYP4F2CYP4A11RET | |
| SCHEMBL30540772 | 0.80 | RET (0.34) | ATRCYP4F2CYP4A11RET | |
| SCHEMBL31190602 | 0.80 | CYP4F2 (0.44) | ATRCYP4F2CYP4A11 | |
| SCHEMBL31190796 | 0.79 | P2RX7 (0.38) | CYP4F2CYP4A11RETMAP3K5 | |
| SCHEMBL31190729 | 0.79 | CYP4F2 (0.37) | CYP4F2CYP4A11PIK3CDPIK3CAPIK3CB | |
| SCHEMBL31190681 | 0.78 | CYP4F2 (0.35) | CYP4F2CYP4A11RETMAP3K5 | |
| SCHEMBL31484985 | 0.77 | RET (0.35) | CYP4F2CYP4A11RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119183452-A | LRRK2 inhibitors | 布雷宁疗法公司 | 2024-12-24 | — | — | CN | disclosed |