SCHEMBL30540804

SCHEMBL30540804

O=C(OC1CC1)c1ccc(O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.58
SCN1A P35498 2/20 0.53
SCN2A Q99250 2/20 0.53
SCN3A Q9NY46 2/20 0.53
CA12 O43570 3/20 0.52
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA7 P43166 3/20 0.52
CA9 Q16790 3/20 0.52
CA14 Q9ULX7 3/20 0.52
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
STS P08842 4/20 0.50
MAPT P10636 3/20 0.50
KMT2A Q03164 3/20 0.49
MAPK1 P28482 1/20 0.49
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
PTPN2 P17706 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777809 1.00 SERPINE1 (0.58) SERPINE1SCN1ASCN2ASCN3ACA12
SCHEMBL9421310 1.00 SERPINE1 (0.58) SERPINE1SCN1ASCN2ASCN3ACA12
SCHEMBL767676 0.93 SERPINE1 (0.51) SERPINE1SCN1ASCN2ASCN3ACA12
SCHEMBL767675 0.93 SERPINE1 (0.51) SERPINE1SCN1ASCN2ASCN3ACA12
SCHEMBL29283750 0.92 STS (0.59) SERPINE1SCN1ASCN2ASCN3ACA12
SCHEMBL27613024 0.91 SERPINE1 (0.61) SERPINE1SCN1ASCN2ASCN3ASTS
SCHEMBL6298658 0.90 STS (0.60) SERPINE1SCN1ASCN2ASCN3ACA12
SCHEMBL4242989 0.90 STS (0.60) SERPINE1SCN1ASCN2ASCN3ACA12
SCHEMBL6298568 0.90 STS (0.60) SERPINE1SCN1ASCN2ASCN3ACA12
SCHEMBL9895375 0.89 ESR2 (0.50) SERPINE1SCN1ASCN2ASCN3ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111170941-B Preparation method of 1-cyclopropyl-6, 7-difluoro-8-methoxy fluoroquinolone-3-carboxylic acid ester 江西农业大学 2023-07-25 CN disclosed