Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 13/20 | 0.58 |
| ▸ | CDK4 | P11802 | 10/20 | 0.58 |
| ▸ | CDK6 | Q00534 | 18/20 | 0.49 |
| ▸ | PIM1 | P11309 | 3/20 | 0.47 |
| ▸ | CCND3 | P30281 | 7/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.47 |
| ▸ | CDK1 | P06493 | 5/20 | 0.47 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CCNH | P51946 | 1/20 | 0.45 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30541017 | 0.84 | CDK6 (0.62) | CCND1CDK4CDK6PIM1CCND3 | |
| SCHEMBL30541018 | 0.84 | CDK6 (0.68) | CCND1CDK4CDK6PIM1CCND3 | |
| SCHEMBL30541020 | 0.84 | CCND1 (0.57) | CCND1CDK4CDK6PIM1CCND3 | |
| SCHEMBL30541042 | 0.82 | CDK6 (0.60) | CCND1CDK4CDK6CCND3CCNA2 | |
| SCHEMBL30541156 | 0.80 | CDK6 (0.60) | CCND1CDK4CDK6CCND3CCNA2 | |
| SCHEMBL30541013 | 0.80 | CDK4 (0.61) | CCND1CDK4CDK6PIM1CCND3 | |
| SCHEMBL25284651 | 0.74 | CCND1 (1.00) | CCND1CDK4CDK6 | |
| SCHEMBL17488665 | 0.73 | CDK4 (0.65) | CCND1CDK4CDK6PIM1CCND3 | |
| SCHEMBL30541021 | 0.72 | CDK6 (0.62) | CCND1CDK4CDK6PIM1CCND3 | |
| SCHEMBL30541009 | 0.72 | CDK6 (0.68) | CCND1CDK4CDK6PIM1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583283-A | CDK inhibitors and their use as pharmaceuticals | 普莱鲁德疗法有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-116583283-A | CDK inhibitors and their use as pharmaceuticals | 普莱鲁德疗法有限公司 | 2023-08-11 | — | — | CN | disclosed |